On July 27, 2010, the Mac Pro was updated with Intel Xeon processors based on the Nehalem/Westmere architectures, and 'speed bumped' again in mid- 2012.

This was replaced by a quad-core Xeon Clovertown model on April 4, 2007, and again on Januby a quad-core Xeon Harpertown model.

The first Mac Pro was based on twin dual-core Xeon Woodcrest processors. An Intel-based replacement for those machines had been expected for some time before the Pro was formally announced on Augat Apple's annual Worldwide Developers Conference. Outwardly, the first generation Mac Pro resembled the last version of the Power Mac G5, and has similar expansion capabilities. As of 2022, the Mac Pro is the last computer from Apple to have not yet made the transition to Apple Silicon. The Mac Pro, in most configurations, was the fastest computer that Apple offered, and is one of four desktop computers in the current Macintosh lineup, the others being the iMac, the Mac mini, and the Mac Studio. The Mac Pro is a series of Intel Xeon-based workstation computers manufactured by Apple Inc.

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